时间：6月20日星期五晚上19：30
地点：浙大紫金港校区CAD&CG国家重点实验室402室
报告人: Prof. Danny Chen
主持人：陈为  教授
Title：The Power of Algorithms: Solving Biomedical Imaging Problems
Abstract：In this talk, we discuss our recent research algorithm work and findings on studying biomedical imaging problems and their application to various diseases. First, we show how density-based clustering patterns of dendritic cells in images of lymph nodes are related to the status and prognosis of breast cancer. Second, we propose a new model of Voronoi diagram, called clustering induced Voronoi diagram (CIVD), to study the collective influence of clustered objects to their surrounding areas, and present efficient approximation algorithms for several types of CIVD problems in the d-D space (for any positive constant integer d). Third, we show that with a CIVD model, we can capture the "context" of immune cells in a quantitative manner, which helps identify immune cells on H&E staining images with much improved accuracy, for the study of bowel inflammation diseases. H&E staining images are routinely used in clinical practice. Our studies may reveal possible connections between the clustering of immune cells and the functionality of the immune system, and lay a key foundation for the diagnosis and prognosis of different diseases. Other biomedical imaging results in our studies will also be presented.
Bio：Dr. Danny Ziyi Chen received the B.S. degrees in Computer Science and in Mathematics from the University of San Francisco, California, USA in 1985 and the M.S. and Ph.D. degrees in Computer Science from Purdue University, West Lafayette, Indiana, USA in 1988 and 1992, respectively. He has been on the faculty of the Department of Computer Science and Engineering at the University of Notre Dame, Indiana, USA since 1992, and is currently a full Professor.  Dr. Chen's main research interests are in computational biomedicine, biomedical imaging, computational geometry, algorithms and data structures, VLSI, and data mining.  He has published over 280 journal and conference papers in these areas. He also holds 5 US patents for technology development in computer science and engineering and biomedical applications.
Dr. Chen is a Fellow of IEEE.  He received the CAREER Award of the US National Science Foundation (NSF) in 1996, the James A. Burns, C.S.C. Award for Graduate Education of the University ofNotre Dame in 2009, and was selected as a Laureate in the 2011 Computerworld Honors Program for the work of his team on "Arc-Modulated Radiation Therapy".